The extended immobilisation related with COVID-19 an infection and the restrictions imposed by the pandemic have decided main modifications in bodily exercise and consuming habits, with a adverse influence on bodily efficiency.
Resistance train is often regarded as the strongest safety towards sarcopenia (age associated progressive lack of muscle mass). Plus protein consumption of 1.0–1.3 g/kg/day helps keep muscle mass and operate. Also, supplementation with probiotics is really helpful to facilitate the absorption of important amino acids.
The present research was due to this fact performed to watch non-pharmacological interventions – weight loss program therapy and probiotics – alongside train, in managing sarcopenia for sufferers with latest SARS-CoV-2 historical past (14 days).
The probiotic complement contained 6 bacterial strains (Enterococcus faecium, Lactobacillus acidophilus, Lactobacillus brevis, Lactococcus lactis, Bifidobacterium bifidum, and Bifidobacterium lactis), no less than 10 bn organisms per portion = 4 g (from AllergoSan Institute, Austria).
After two months of hyper protein weight loss program with probiotics, a major enchancment of skeletal muscle index (SMI) was noticed. Moreover, after the therapeutic intervention, the typical worth of two metabolic parameters Alb (low ranges of which point out kidney illness, liver illness, irritation or infections) and Hb (a widely known biomarker for anemia and dietary standing) within the group with weight loss program therapy and probiotics elevated considerably, indicating an enchancment within the basic situation of the sufferers.
The authors conclude: “Diet therapy, consisting of increased protein intake and specific probiotics in muscle anabolism, along with adequate physical training, has demonstrated its role in improving SMI… Significant differences were reported in the improvement of the sarcopenic index values in patients who were recommended an additional intake of proteins and probiotics.
“More research to verify these outcomes and elucidate the mechanism via which some probiotics can affect sarcopenia are essential. Understanding how particular dietary interventions related with probiotics can stop muscle loss can assist enhance the scientific and therapeutic administration of contaminated sufferers with the intention to scale back the well being penalties of COVID-19.”
A prospective study was performed on 200 patients (aged 67.43 ± 7.94 years), with A SPPB score of less than 9 (the Short Physical Performance Battery Protocol and Score Sheet Questionnaire considers ability to rise from a chair, balance, and walking speed).
The recruited patients had a positive COVID-19 test in the 14 days prior.
Participants were randomly divided into: Group K—DP with dietary therapy (protein 1.2–1.5 g/kg) and probiotics for two months; and Group K—non-DP (107 patients) without diet therapy and probiotics.
All patients were included in a specific physical training program (40 min), three sessions per week. Skeletal muscle index (SMI), serum albumin, and hemoglobin were determined.
Those receiving probiotics were given a 4g sachet dissolved in 125 mL of water to consumer in the morning on an empty stomach or in the evening before going to bed.
After two months, a significant difference between initial and final SMI values was determined for the treatment group.
In Group K—DP, at end of study, there were more patients with normal SMI (n = 32 → N = 70) values and fewer sarcopenia patients.
The initial serum albumin showed values in the two groups were not statistically significantly different but the hemoglobin level improved significantly in the treatment group.
The authors note limitations of this study include that protein intake could not be tracked with great accuracy because the recommendation of protein supplementation was not strictly supervised and the adherence to the physical training program was not monitored. Furthermore, the incidence of diabetes was not evaluated.
https://doi.org/10.3390/nu14214701 (registering DOI)
“The Contribution of Diet Therapy and Probiotics within the Treatment of Sarcopenia Induced by Prolonged Immobilization Caused by the COVID-19 Pandemic”
Nistor-Cseppento, C.D.; Moga, T.D.; Bungau, A.F.; Tit, D.M.; Negrut, N.; Pasca, B.; Bochis, C.F.; Ghitea, T.C.; Jurcau, A.; Purza, A.L.; Uivarosan, D.